Monday, December 30, 2013

Coming up to speed with MtDNA

I received my Full Sequence MtDNA results in December. Of course I had no matches at this level, because so few people have tested at this level. I saw a figure of about 18,000 testers at the full sequence level (this number is probably outdated by one year or so). I would need a large number of Nicaraguans testing to find a close match at his level.
I've done a lot of research on the L2a1, and specifically the F subclade. L Haplo is African and about 55,000 years old. I found out that subclade F is anywhere from 2,000 to 10,000 years old. As you can imagine this subclade could travel far and wide throughout Africa over thousands of years. It is widespread in Northern and Central Africa, and made in roads into the Middle East. It is found in Saudi Arabia, and seems to have been spread into Europe by the Jews.
Example 1
We do now have Nicaraguans testing with Family Tree DNA, and I hope to have a close match at some point.
My results mismatched the L2a1f subclade by two mutations, and I have a number of extra mutations. It looks like this will lead to another subclade, which may eventually lead to a more specific location of origin for my ancestors.
Example 2
I've been attending the new series of webinars presented by Family Tree DNA. The MtDNA session was so enlightening! I really had no idea how to read the results page. Example 2 shows the mutations, or differences, I have in my DNA from the Reference model used. These mutations occur among individuals and are disseminated throughout a population through the generations. In earlier eras, when migration was less frequent, these mutations would be limited to individuals living in a small region. Example 2 shows a letter before and after the number. The first letter represents the reference model, and the second represents our own difference from this reference. For example the first position here is A16129G, and we see the first letter is A and the last G . Position 16129 is A in the reference, and is G in my own sequence. These differences are used to place everyone into a Haplo group and subclades. A and G often shift positions, along with C and T.
I found another site besides Mitosearch and Sorenson to upload my full sequence results and compare; namely the MtDNA I found one match there. Not an exact match so we probably share an ancestors hundreds or thousands of years ago.
My best hope for a breakthrough with MtDNA would be a perfect match. I also hope we had a mutation in my line fairly recently, because that would mean we share an ancestor in the genealogical time frame.


Lucimar gomes da silva florentino said...

Congratulations dear Annette

Lucimar gomes da silva florentino said...
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Lucimar gomes da silva florentino said...
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